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Depo-Provera FAQ
What is the link between Depo-Provera and brain tumors?
Studies show that long-term Depo-Provera use increases meningioma (brain tumor) risk by up to 500%. In January 2026, the FDA required updated labeling to warn about this risk.
What is the Depo-Provera MDL?
In February 2025, federal lawsuits were consolidated into MDL No. 3126 in the Middle District of Florida. Over 1,300 cases are pending against Pfizer.
Based on the landmark French ANSM study (5.6x risk increase), 2026 BMJ findings, and Pfizer's 'Black Box' meningioma warning updates.